Requirements for dose calculation on an active scanned proton beamline for small, shallow fields

• Published in: Physica medica 2023-09, Vol.113, p.102659, Article 102659
• Main Authors: Knäusl, B., Langgartner, L., Stock, M., Janson, M., Furutani, K.M., Beltran, C.J., Georg, D., Resch, A.F.
• Format: Article
• Language: English
• Subjects: Eye Neoplasms; Humans; Monte Carlo simulations; Ocular treatments; Plastics; Pre-clinical research; Proton Therapy; Protons; Small field dosimetry; Synchrotrons
• ISSN: 1120-1797; 1724-191X; 1724-191X
• DOI: 10.1016/j.ejmp.2023.102659

A growing interest in using proton pencil beam scanning in combination with collimators for the treatment of small, shallow targets, such as ocular melanoma or pre-clinical research emerged recently. This study aims at demonstrating that the dose of a synchrotron-based PBS system with a dedicated small, shallow field nozzle can be accurately predicted by a commercial treatment planning system (TPS) following appropriate tuning of both, nozzle and TPS. A removable extension to the clinical nozzle was developed to modify the beam shape passively. Five circular apertures with diameters between 5 to 34mm, mounted 72cm downstream of a range shifter were used. For each collimator treatment plans with spread-out Bragg peaks (SOBP) with a modulation of 3 to 30mm were measured and calculated with GATE/Geant4 and the research TPS RayStation (RS11B-R). The dose grid, multiple coulomb scattering and block discretization resolution were varied to find the optimal balance between accuracy and performance. For SOBPs deeper than 10mm, the dose in the target agreed within 1% between RS11B-R, GATE/Geant4 and measurements for aperture diameters between 8 to 34mm, but deviated up to 5% for smaller apertures. A plastic taper was introduced reducing scatter contributions to the patient (from the pipe) and improving the dose calculation accuracy of the TPS to a 5% level in the entrance region for large apertures. The commercial TPS and GATE/Geant4 can accurately calculate the dose for shallow, small proton fields using a collimator and pencil beam scanning. •TPS and GATE accurately calculate the dose for small, shallow collimated proton fields.•5 mm fields can be irradiated with a scanned proton beam and a passive beam modifier.•Ocular and pre-clinical proton irradiations do not require a dedicated infrastructure.