Electrocardiographic changes after balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension: Data from the Hellenic Registry

Balloon pulmonary angioplasty (BPA) has provided an effective invasive treatment for inoperable patients with chronic thromboembolic pulmonary hypertension (CTEPH). The hemodynamic improvement achieved by BPA has significantly increased the long-term prognosis of these patients, mostly by reversing...

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Published in:Journal of electrocardiology 2023-11, Vol.81, p.26-31
Main Authors: Kariki, Ourania, Karyofyllis, Panagiotis, Mililis, Panagiotis, Saplaouras, Athanasios, Dragasis, Stylianos, Chatziantoniou, Anastasios, Alexiou, Dimitris, Patsiotis, Ilias G., Letsas, Konstantinos P., Efremidis, Michael
Format: Article
Language:English
Subjects:
Angioplasty, Balloon - adverse effects
Balloon pulmonary angioplasty
Chronic Disease
Chronic thromboembolic pulmonary hypertension
ECG
Electrocardiography
Hemodynamics
Humans
Hypertension, Pulmonary
Pulmonary Artery
Pulmonary Embolism - complications
Pulmonary Embolism - therapy
RV strain pattern
Treatment Outcome
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Summary:Balloon pulmonary angioplasty (BPA) has provided an effective invasive treatment for inoperable patients with chronic thromboembolic pulmonary hypertension (CTEPH). The hemodynamic improvement achieved by BPA has significantly increased the long-term prognosis of these patients, mostly by reversing the negative remodeling of the right ventricle (RV). In a cohort of 17 patients with symptomatic CTEPH hemodynamic data were collected before and after the completion of BPA sessions. After the confirmation of statistically significant hemodynamic improvement, we examined the changes in certain prespecified electrocardiographic (ECG) parameters (PR interval duration, QRS duration, QTc interval duration, R wave and S wave amplitude in lead I, R wave and S wave amplitude in precordial leads V1, V5 and V6) before the initiation and one month after the completion of BPA sessions. In addition, ECGs were qualitatively assessed before and after treatment for the presence of ECG abnormalities related to PH, proposed by the guidelines of the European Society of Cardiology (ESC). The term ESC criteria 1–6 was used for their description. Statistically significant correlation (p 
ISSN:0022-0736
1532-8430
DOI:10.1016/j.jelectrocard.2023.07.006