The microbial profile of infected endoprosthetic reconstructions after wide excision for patients with musculoskeletal tumors: A call for pathogen‐based practices

Background and ObjectivesPeriprosthetic infection is a devastating complication following endoprosthetic reconstruction. This study utilized a large database of endoprostheses to describe the incidence, risk factors, and microbial profile of such infections to better catalogue and understand these c...

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Bibliographic Details
Published in:Journal of surgical oncology 2023-12, Vol.128 (8), p.1437-1445
Main Authors: Trikha, Rishi, Greig, Danielle, Sekimura, Troy, Geiger, Erik J., Wessel, Lauren, Eckardt, Jeffrey J., Bernthal, Nicholas M.
Format: Article
Language:English
Subjects:
Bone cancer
Cancer surgery
Infections
Muscular system
Musculoskeletal system
Pathogens
Reconstructive surgery
Tumors
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Summary:Background and ObjectivesPeriprosthetic infection is a devastating complication following endoprosthetic reconstruction. This study utilized a large database of endoprostheses to describe the incidence, risk factors, and microbial profile of such infections to better catalogue and understand these catastrophic events.MethodsA retrospective review of endoprosthetic reconstructions for an oncologic indication from January 1, 1981 to December 31, 2020 was performed. Demographic, oncologic, procedural and outcome data was analyzed. Multivariable logistic regression was used to identify potential risk factors for infection with significance defined as p 
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.27428