Absorbed dose evaluation of a blood irradiator with alanine, TLD-100 and ionization chamber

Irradiation of blood bags using X-ray irradiators and dosimetry services are required to ensure uniform dose levels in the range 25–50 Gy to prevent Transfusion Associated Graft versus Host Disease (TA-GvHD). An absorbed dose characterization of a Raycell MK2 X-Irradiator was performed using three d...

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Bibliographic Details
Published in:Applied radiation and isotopes 2023-10, Vol.200, p.110981-110981, Article 110981
Main Authors: Grasso, S., Varallo, A., Ricciardi, R., Italiano, M.E., Oliviero, C., D'Avino, V., Feoli, C., Ambrosino, F., Pugliese, M., Clemente, S.
Format: Article
Language:English
Subjects:
Alanine
Blood irradiation X-Ray irradiator
Dose mapping
Ion chamber
Raycell MK2
TLD dosimetry
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Summary:Irradiation of blood bags using X-ray irradiators and dosimetry services are required to ensure uniform dose levels in the range 25–50 Gy to prevent Transfusion Associated Graft versus Host Disease (TA-GvHD). An absorbed dose characterization of a Raycell MK2 X-Irradiator was performed using three different dosimetric systems. Results showed a dosimetric accuracy of the ionization chamber together with the Alanine dosimeter. TLDs measurements exhibited a small overestimation by 4% of the absorbed dose. The Dose Uniformity Ratio (DUR), between maximum and minimum dose levels in the canister, was in good agreement with the manufacturer specifications (≤1.5). •Irradiation of blood bags using X-ray irradiators.•Fine dose absolute characterization of a Raycell MK2 X-Irradiator.•Absolute dose at operative conditions using an Alanine dosimeter phantom.•An ionization chamber and LiF:Mg,Ti TLDs dosimeters.
ISSN:0969-8043
1872-9800
DOI:10.1016/j.apradiso.2023.110981