Fact‐finding survey on assisted reproductive technology in Japan

AimsIn anticipation of the future development of assisted reproductive technology (ART) and to smoothly introduce new technology, it is necessary to understand the current staffing status of the medical system and the current state of treatment, as well as the status of in vitro fertilization add‐on...

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Published in:The journal of obstetrics and gynaecology research 2023-11, Vol.49 (11), p.2593-2601
Main Authors: Harada, Sayaka, Yamada, Mitsutoshi, Shirasawa, Hiromitsu, Jwa, Seung Chik, Kuroda, Keiji, Harada, Miyuki, Osuga, Yutaka
Format: Article
Language:English
Subjects:
Embryo transfer
Endometritis
Endometrium
Freeze-thawing
Hatching
In vitro fertilization
Medical personnel
Microbiomes
Ovaries
Reproductive technologies
Workforce planning
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Summary:AimsIn anticipation of the future development of assisted reproductive technology (ART) and to smoothly introduce new technology, it is necessary to understand the current staffing status of the medical system and the current state of treatment, as well as the status of in vitro fertilization add‐ons, where the need for insurance coverage is currently a matter of debate.MethodsART facilities in Japan were surveyed (437 valid responses, response rate: 71%). Current staffing status of the medical system, implementation rates of ART, add‐on treatments, and medical supplies were investigated.ResultsDespite the abundance of embryologists, nurses, and obstetricians and gynecologists in facilities, the majority of facilities lacked counselors, anesthesiologists, and other essential medical professionals. Conventional ovarian stimulation was widely adopted (median 120 [interquartile range 60–300] cycles), followed by mild ovarian simulation (60 [30–200]). Additionally, freeze–thaw embryo transfer cycles (300 [120–750]) were performed more frequently than fresh embryo transfer cycles (30 [30–60]). Among the add‐ons, assisted hatching (85.1%), chronic endometritis examination (77.2%) and treatment (76.9%), artificial oocyte activation (67.3%), endometrial receptivity analysis (64.2%), and endometrial microbiome analysis (58.9%) were relatively widely employed.ConclusionsThe implementation of frozen–thawed embryo transfer cycles, freeze‐all strategies, and add‐on treatments have become popular and widely accepted despite the lack of robust evidence regarding their safety and efficacy.
ISSN:1341-8076
1447-0756
DOI:10.1111/jog.15780