A cross-sectional study to evaluate utility measure and health-related quality of life (HRQoL) among patients with severe uncontrolled asthma in Spain

The utility measure is a method to quantify health-related quality of life according to the preference values that patients attach to their health status. This study aimed to estimate the utility measure of patients with controlled and uncontrolled severe asthma (SA) in Spain, separately. Additional...

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Bibliographic Details
Published in:The Journal of asthma 2024, Vol.61 (1), p.27-38
Main Authors: Martínez Moragón, Eva, Entrenas Costa, Luis Manuel, Sánchez-Covisa Hernández, Joaquín, de Prado Moncusí, Anna, Monteagudo Ruiz, Gema
Format: Article
Language:English
Subjects:
Asthma - therapy
Cross-Sectional Studies
Female
Health Status
Humans
Male
Quality of Life
Spain
Surveys and Questionnaires
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Summary:The utility measure is a method to quantify health-related quality of life according to the preference values that patients attach to their health status. This study aimed to estimate the utility measure of patients with controlled and uncontrolled severe asthma (SA) in Spain, separately. Additionally, other characteristics (sociodemographic, clinical, and healthcare resource use [HCRU]) were also assessed for both SA populations. This cross-sectional study included 159 patients with SA in Spain. Data were collected from medical records and directly from the patients during the study visit. Asthma Control Questionnaire (ACQ)-5 was used to classify patients with controlled and uncontrolled SA. Most of the patients were female (72.0% uncontrolled SA and 63.6% controlled SA). The mean ( ) EuroQol-5D (EQ-5D-5L) score was 0.88 (0.14) and 0.70 (0.25) in controlled and uncontrolled SA, respectively. The mean ( ) Asthma Quality-of-Life-5D (AQL-5D) score was 0.93 (0.09) and 0.85 (0.09) in controlled and uncontrolled SA, respectively. Emergency visits (19.2 2.7%) and hospitalizations (7.7% no hospitalization) were more common among uncontrolled SA than controlled SA. Mean ( ) number of visits to primary care and pneumologists in uncontrolled SA controlled SA was 4.1 (2.8) 2.5 (3.0) and 3.7 (3.5) 2.8 (2.2), respectively. The study provides data on utility measures among patients with SA in Spain for the first time. Patients with uncontrolled SA had lower HRQoL and higher HCRU than patients with controlled SA. Therefore, the implementation of measures that improve HRQoL among patients with uncontrolled SA is highly recommended.
ISSN:0277-0903
1532-4303
DOI:10.1080/02770903.2023.2241891