Pediatric Traumatic Brain Injury: Impact on the Developing Brain

Traumatic brain injury (TBI) is a serious public health concern impacting millions of children and adolescents each year. Experiencing a brain injury during key critical periods of brain development can affect the normal formation of brain networks that are responsible for a range of complex neuroco...

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Bibliographic Details
Published in:Pediatric neurology 2023-11, Vol.148, p.215-222
Main Authors: Blackwell, Laura S., Grell, Robert
Format: Article
Language:English
Subjects:
Developmental
Management
Neurocognitive
Neuroplasticity
Outcomes
Pediatric
Traumatic brain injury
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Summary:Traumatic brain injury (TBI) is a serious public health concern impacting millions of children and adolescents each year. Experiencing a brain injury during key critical periods of brain development can affect the normal formation of brain networks that are responsible for a range of complex neurocognitive outcomes. In addition, there are multiple pre- and postinjury factors that influence the trajectory of recovery and outcomes. In this review, we will focus on the current state of the literature within pediatric TBI; systematically review the available research on developmental aspects of TBI in children, focusing on the pathophysiology of the injury and its impact on the developing brain; and highlight knowledge gaps for further exploration.
ISSN:0887-8994
1873-5150
DOI:10.1016/j.pediatrneurol.2023.06.019