Prognosis of pancreaticoduodenectomy in octogenarians for pancreatic ductal adenocarcinoma with propensity score matched analysis

Background This retrospective study investigates factors affecting surgical and oncological outcome after performing pancreaticoduodenectomy in octogenarian patients diagnosed with pancreatic ductal adenocarcinoma. Methods From January 2009 to December 2018, patients who underwent pancreaticoduodene...

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Bibliographic Details
Published in:ANZ journal of surgery 2023-11, Vol.93 (11), p.2655-2663
Main Authors: Jeong, HyeJeong, Lim, Soo Yeun, Jeon, Hyun Jeong, Yoon, So Jeong, Kim, Hongbeom, Han, In Woong, Heo, Jin Seok, Shin, Sang Hyun
Format: Article
Language:English
Subjects:
Adenocarcinoma
Aged, 80 and over
Carcinoma, Pancreatic Ductal - surgery
Complications
Health services
Humans
Medical prognosis
octogenarian
Octogenarians
Pancreas
Pancreatic cancer
pancreatic ductal adenocarcinoma
Pancreatic Neoplasms
Pancreatic Neoplasms - pathology
Pancreaticoduodenectomy
Patients
Prognosis
Propensity Score
propensity score matching
Retrospective Studies
Survival
Treatment Outcome
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Summary:Background This retrospective study investigates factors affecting surgical and oncological outcome after performing pancreaticoduodenectomy in octogenarian patients diagnosed with pancreatic ductal adenocarcinoma. Methods From January 2009 to December 2018, patients who underwent pancreaticoduodenectomy for pancreatic ductal adenocarcinoma were included. Data were analysed by comparing clinicopathological characteristics, complications, survival, recurrence, adjuvant treatment between octogenarians and the younger group. Propensity score matched analysis was performed due to the small size of the octogenarian group. Results A total of 666 patients were included in this study and 24 (3.6%) were included in the octogenarian group. Short term complication rates (P = 0.119) and hospital stay (P = 0.839) did not differ between two groups. Overall survival between the two groups showed significant difference (
ISSN:1445-1433
1445-2197
DOI:10.1111/ans.18679