Vertebral bone quality score for opportunistic osteoporosis screening: a correlation and optimal threshold analysis

Purpose This study investigated the vertebral bone quality (VBQ) score as a potential tool for opportunistic osteoporosis screening and its correlation with dual-energy X-ray absorptiometry (DXA) values. Methods In a single-center retrospective cohort of 130 patients, VBQ and DXA measures were compa...

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Bibliographic Details
Published in:European spine journal 2023-11, Vol.32 (11), p.3906-3911
Main Authors: Özmen, Emre, Biçer, Ozancan, Meriç, Emre, Circi, Esra, Barış, Alican, Yüksel, Serdar
Format: Article
Language:English
Subjects:
Bone density
Dual energy X-ray absorptiometry
Medicine
Medicine & Public Health
Neurosurgery
Original Article
Osteoporosis
Statistical analysis
Surgical Orthopedics
Vertebrae
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Summary:Purpose This study investigated the vertebral bone quality (VBQ) score as a potential tool for opportunistic osteoporosis screening and its correlation with dual-energy X-ray absorptiometry (DXA) values. Methods In a single-center retrospective cohort of 130 patients, VBQ and DXA measures were compared using various statistical analyses. The optimal VBQ threshold for predicting osteoporosis was determined using receiver operating characteristic (ROC) analysis. Results VBQ exhibited a significant negative association with DXA values, suggesting that higher VBQ scores are indicative of lower bone density. Age and VBQ were significant predictors of osteoporosis, with both increasing the log-odds of the condition. An optimal VBQ threshold of 2.7 was determined, demonstrating fair discriminatory power and high negative predictive value. Conclusion The study highlighted the potential of VBQ as a diagnostic tool for osteoporosis with high intra- and inter-observer reliability. The optimal VBQ threshold of 2.7 can aid in ruling out osteoporosis and identifying individuals for further evaluation.
ISSN:0940-6719
1432-0932
DOI:10.1007/s00586-023-07912-0