Left atrial strain as a predictor of left ventricular filling pressures in coronary artery disease with preserved ejection fraction: a comprehensive study with left ventricular end-diastolic and pre-atrial contraction pressures

Assessing left ventricular (LV) filling pressure (LVFP) is challenging in patients with coronary artery disease (CAD) and preserved LV ejection fraction (LVEF). We aimed to correlate left atrial strain (LAS) with two invasive complementary parameters of LVFP and compared its accuracy to other echoca...

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Bibliographic Details
Published in:The international journal of cardiovascular imaging 2023-11, Vol.39 (11), p.2193-2204
Main Authors: Nishida, Gustavo, Calvilho Junior, Antonio Amador, Assef, Jorge Eduardo, dos Santos, Natasha Soares Simões, de Andrade Vilela, Andrea, Braga, Sergio Luiz Navarro
Format: Article
Language:English
Subjects:
Algorithms
Blood pressure
Cardiac Imaging
Cardiology
Cardiovascular disease
Contractility
Coronary artery disease
Coronary vessels
Diastolic pressure
Echocardiography
Ejection fraction
Heart
Heart diseases
Imaging
Medicine
Medicine & Public Health
Original Paper
Parameter identification
Radiology
Vein & artery diseases
Ventricle
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Summary:Assessing left ventricular (LV) filling pressure (LVFP) is challenging in patients with coronary artery disease (CAD) and preserved LV ejection fraction (LVEF). We aimed to correlate left atrial strain (LAS) with two invasive complementary parameters of LVFP and compared its accuracy to other echocardiographic data to predict high LVFP. This cross-sectional, single-center study enrolled 81 outpatients with LVEF > 50% and significant CAD from a database. Near-simultaneous echocardiography and invasive measurements of both LV end-diastolic pressure (LVEDP) and LV pre-atrial contraction (pre-A) pressure were performed in each patient, based on the definition of LVEDP > 16 mmHg and LV pre-A > 12 mmHg as high LVFP. A moderate to strong correlation was observed between LAS reservoir (LASr), contractile strain, and LVEDP (r: 0.67 and 0.62, respectively; p 
ISSN:1875-8312
1569-5794
1875-8312
1573-0743
DOI:10.1007/s10554-023-02938-3