Cognition in patients with post‐bariatric hypoglycemia

Objective Bariatric surgery, a highly effective treatment for obesity and associated comorbidities, may improve cognition and brain volume in parallel with cardiometabolic function. However, some post‐bariatric individuals develop post‐bariatric hypoglycemia (PBH), which can be frequent and severe....

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Bibliographic Details
Published in:Obesity (Silver Spring, Md.) Md.), 2024-03, Vol.32 (3), p.466-471
Main Authors: Puleio, Alexa, Sheehan, Amanda, Musen, Gail, Patti, Mary Elizabeth
Format: Article
Language:English
Subjects:
Adult
Adults
Bariatric Surgery - adverse effects
Body mass index
Brain research
Cognition
Cognition & reasoning
Consciousness
Dementia
Diabetes
Dumping syndrome
Executive function
Fainting
Gastric Bypass - adverse effects
Gastrointestinal surgery
Glucose monitoring
Humans
Hypoglycemia
Hypoglycemia - etiology
Memory
Obesity
Obesity, Morbid - complications
Obesity, Morbid - surgery
Semantics
Weight control
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Summary:Objective Bariatric surgery, a highly effective treatment for obesity and associated comorbidities, may improve cognition and brain volume in parallel with cardiometabolic function. However, some post‐bariatric individuals develop post‐bariatric hypoglycemia (PBH), which can be frequent and severe. The impact of recurrent hypoglycemia on cognition in PBH is unknown. The objective of this study was to determine whether individuals with PBH display reduced cognitive function compared with postsurgical counterparts without hypoglycemia. Methods Fourteen adults with a history of Roux‐en‐Y gastric bypass with hypoglycemia (PBH+, n = 7) or without PBH (PBH−, n = 7) completed assessments of memory, executive function, attention, and psychomotor speed. Results PBH+ individuals displayed significantly decreased performance in category fluency (p 
ISSN:1930-7381
1930-739X
1930-739X
DOI:10.1002/oby.23862