Post-dynamic, isometric and combined resistance exercise responses in medicated hypertensive men

• Published in: Journal of human hypertension 2024-01, Vol.38 (1), p.52-61
• Main Authors: Oliveira-Silva, Laura, Fecchio, Rafael Yokoyama, Silva Junior, Natan Daniel da, Pio-Abreu, Andrea, Silva, Giovânio Vieira da, Drager, Luciano Ferreira, Silva de Sousa, Julio Cesar, Forjaz, Cláudia Lúcia de Moraes
• Format: Article
• Language: English
• Subjects: 692/699/75/243; 692/700/459; Baroreceptors; Blood pressure; Blood Pressure - physiology; Cardiovascular System; Clinical trials; Epidemiology; Hand Strength - physiology; Health Administration; Heart Rate - physiology; Hemodynamics; Humans; Hypertension - diagnosis; Hypertension - drug therapy; Hypotension; Male; Medicine; Medicine & Public Health; Muscle contraction; Public Health; Reflexes; Resistance Training; Skeletal muscle; Vasodilation
• ISSN: 1476-5527; 0950-9240; 1476-5527
• DOI: 10.1038/s41371-023-00859-1

This study investigated the effects of dynamic resistance exercise (DRE), isometric handgrip exercise (IHE) and combined resistance exercise (DRE+IHE) on post-exercise hypotension (PEH) and its hemodynamic, autonomic, and vascular mechanisms. For that, 70 medicated hypertensives men (52 ± 8 years) were randomly allocated to perform one of the following interventions: DRE (3 sets, 8 exercises, 50% of 1RM), IHE (4 sets, 2 min, 30% of MVC), CRE (DRE+IHE) and control (CON, seated rest). Before and after the interventions, blood pressure (BP), systemic hemodynamics, cardiovascular autonomic modulation and brachial vascular parameters were evaluated. After the DRE and CRE, systolic and mean BP decreased (SBP = −7 ± 6 and −8 ± 8 mmHg; MBP −4 ± 5 and −5 ± 5 mmHg, respectively, all P