Impact of Chronic Coronary Artery Disease and Revascularization Strategy in Patients with Severe Aortic Stenosis Who Underwent Transcatheter Aortic Valve Implantation

The prognostic impact of coronary artery disease (CAD) after transcatheter aortic valve implantation (TAVI) is controversial. The aim of this study is to investigate the impact of CAD and different revascularization strategies on clinical outcomes in patients who underwent TAVI with third generation...

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Bibliographic Details
Published in:The American journal of cardiology 2023-11, Vol.206, p.14-22
Main Authors: Aurigemma, Cristina, Massussi, Mauro, Fraccaro, Chiara, Adamo, Marianna, D'Errigo, Paola, Rosato, Stefano, Seccareccia, Fulvia, Santoro, Gennaro, Baiocchi, Massimo, Barbanti, Marco, Biancari, Fausto, Baglio, Giovanni, Marcellusi, Andrea, Trani, Carlo, Tarantini, Giuseppe
Format: Article
Language:English
Subjects:
Angioplasty
Aorta
Aortic stenosis
Aortic valve
Cardiology
Cardiovascular disease
Clinical outcomes
Coronary artery disease
Coronary vessels
Enrollments
Heart diseases
Heart rate
Heart valves
Implantation
Missing data
Mortality
Myocardial infarction
Observational studies
Patients
percutaneous coronary intervention
Prostheses
Strategy
Stroke
transcatheter aortic valve replacement
Transplants & implants
Vein & artery diseases
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Summary:The prognostic impact of coronary artery disease (CAD) after transcatheter aortic valve implantation (TAVI) is controversial. The aim of this study is to investigate the impact of CAD and different revascularization strategies on clinical outcomes in patients who underwent TAVI with third generation devices. Patients enrolled in the national observational Observational Study of Effectiveness of SAVR-TAVI Procedures for Severe Aortic Stenosis Treatment II study were stratified according to the presence of CAD (CAD+, n = 1,130) versus no CAD (CAD−, n = 1,505), and compared using a propensity matched analysis. CAD+ group was further stratified according to the revascularization strategy: no revascularization (n = 331), revascularization performed >90 days before index-TAVI (n = 417) and coronary revascularization performed
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2023.08.045