Loading…

Added value of advanced workup after the first seizure: A 7‐year cohort study

Objective This study was undertaken to establish whether advanced workup including long‐term electroencephalography (LT‐EEG) and brain magnetic resonance imaging (MRI) provides an additional yield for the diagnosis of new onset epilepsy (NOE) in patients presenting with a first seizure event (FSE)....

Full description

Saved in:
Bibliographic Details
Published in:Epilepsia (Copenhagen) 2023-12, Vol.64 (12), p.3246-3256
Main Authors: De Stefano, Pia, Ménétré, Eric, Stancu, Patrick, Mégevand, Pierre, Vargas, Maria Isabelle, Kleinschmidt, Andreas, Vulliémoz, Serge, Wiest, Roland, Beniczky, Sandor, Picard, Fabienne, Seeck, Margitta
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective This study was undertaken to establish whether advanced workup including long‐term electroencephalography (LT‐EEG) and brain magnetic resonance imaging (MRI) provides an additional yield for the diagnosis of new onset epilepsy (NOE) in patients presenting with a first seizure event (FSE). Methods In this population‐based study, all adult (≥16 years) patients presenting with FSE in the emergency department (ED) between March 1, 2010 and March 1, 2017 were assessed. Patients with obvious nonepileptic or acute symptomatic seizures were excluded. Routine EEG, LT‐EEG, brain computed tomography (CT), and brain MRI were performed as part of the initial workup. These examinations' sensitivity and specificity were calculated on the basis of the final diagnosis after 2 years, along with the added value of advanced workup (MRI and LT‐EEG) over routine workup (routine EEG and CT). Results Of the 1010 patients presenting with FSE in the ED, a definite diagnosis of NOE was obtained for 501 patients (49.6%). Sensitivity of LT‐EEG was higher than that of routine EEG (54.39% vs. 25.5%, p 
ISSN:0013-9580
1528-1167
DOI:10.1111/epi.17771