Opportunities for prostate-specific membrane antigen hybrid imaging in prostate cancer

Prostate-specific membrane antigen (PSMA) hybrid imaging is a promising new technique gaining importance in the field of prostate cancer (PCa) diagnosis and treatment planning. By combining PSMA radioligands and computed tomography (CT) or magnetic resonance imaging (MRI), PSMA hybrid imaging opens...

Full description

Saved in:
Bibliographic Details
Published in:Urologie (Heidelberg, Germany) Germany), 2023-11, Vol.62 (11), p.1153-1159
Main Authors: Strauß, Anna-Sophie, Bolenz, Christian, Beer, Ambros J, Zengerling, Friedemann, Beer, Meinrad, Miksch, Jonathan
Format: Article
Language:ger
Subjects:
Humans
Male
Positron Emission Tomography Computed Tomography - methods
Positron-Emission Tomography
Prostate - pathology
Prostate-Specific Antigen
Prostatic Neoplasms - pathology
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Prostate-specific membrane antigen (PSMA) hybrid imaging is a promising new technique gaining importance in the field of prostate cancer (PCa) diagnosis and treatment planning. By combining PSMA radioligands and computed tomography (CT) or magnetic resonance imaging (MRI), PSMA hybrid imaging opens up new diagnostic opportunities. PSMA-PET/CT (PET: positron-emission tomography) is already well established in high-risk PCa for primary staging and tumor localization when biochemical recurrence occurs. Further potential indications for PSMA-PET/CT include tumor detection in the initial work-up before a rebiopsy with improved accuracy, the identification of target structures for precise local treatment in recurrent PCa (salvage radiotherapy or radio-guided surgery) as well as a prediction of response to PSMA radioligand therapy. This narrative review is based on a recent literature search and aims to highlight the opportunities of PSMA imaging in different disease stages of PCa.
ISSN:2731-7072
DOI:10.1007/s00120-023-02189-z