Treatment of therapy-resistant verruca plantaris with laser-assisted photodynamic therapy (PDT) with methyl aminolevulinate (MAL)

Mosaic warts are a type of verruca vulgaris that occur almost exclusively on the soles of the feet. They are particularly known for their treatment resistance and high recurrence rate. Laser-assisted drug delivery (LADD) photodynamic therapy (PDT) with methyl aminolevulinate (MAL) offers a low pain...

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Bibliographic Details
Published in:Dermatologie (Heidelberg, Germany) Germany), 2024-01, Vol.75 (1), p.71-74
Main Authors: Nienstedt, Robert, Schlagenhauff, Bettina, Rümmelein, Bettina C
Format: Article
Language:ger
Subjects:
Aminolevulinic Acid - analogs & derivatives
Humans
Lasers, Gas - therapeutic use
Photochemotherapy - adverse effects
Photosensitizing Agents - therapeutic use
Warts - drug therapy
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Summary:Mosaic warts are a type of verruca vulgaris that occur almost exclusively on the soles of the feet. They are particularly known for their treatment resistance and high recurrence rate. Laser-assisted drug delivery (LADD) photodynamic therapy (PDT) with methyl aminolevulinate (MAL) offers a low pain treatment option with hardly any side effects in therapy-resistant cases of verruca plantaris. Pretreatment with an ablative fractional laser is especially important to obtain penetration of MAL through the human papillomavirus (HPV)-infected skin layer.
ISSN:2731-7013
DOI:10.1007/s00105-023-05224-4