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Harmonized standard operating procedures for administering the ALS functional rating scale-revised
The ALS Functional Rating Scale-Revised is the most commonly used primary outcome measure in current ALS clinical trials. While rigorous training and certification is generally recognized as critical to reliable performance, differences have existed between training in the two groups responsible for...
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Published in: | Amyotrophic lateral sclerosis and frontotemporal degeneration 2024-02, Vol.25 (1-2), p.26-33 |
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Main Authors: | , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | The ALS Functional Rating Scale-Revised is the most commonly used primary outcome measure in current ALS clinical trials. While rigorous training and certification is generally recognized as critical to reliable performance, differences have existed between training in the two groups responsible for most training in ALS outcome measures. We present a harmonized standard operating procedure which is intended to further reduce response variability by the use of identical training in North America and Europe. |
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ISSN: | 2167-8421 2167-9223 |
DOI: | 10.1080/21678421.2023.2260832 |