Pathophysiology of Acute Kidney Frailty

Acute kidney frailty is a premorbid condition of diminished renal functional reserve that predisposes to acute kidney injury; this condition results from subclinical wear or distortion of renal homeostatic responses that protect the renal excretory function. Knowledge of its pathophysiological basis...

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Bibliographic Details
Published in:Physiology (Bethesda, Md.) Md.), 2023-11, Vol.38 (6), p.275-284
Main Authors: Sancho-Martínez, Sandra M., López-Hernández, Francisco J.
Format: Article
Language:English
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Summary:Acute kidney frailty is a premorbid condition of diminished renal functional reserve that predisposes to acute kidney injury; this condition results from subclinical wear or distortion of renal homeostatic responses that protect the renal excretory function. Knowledge of its pathophysiological basis is critical for the development of diagnostic and therapeutic strategies that allow for prophylactic intervention and disease prevention.
ISSN:1548-9213
1548-9221
DOI:10.1152/physiol.00011.2023