Interoception: Spinal sensory neurons that innervate the intestines

The gut is innervated by sensory neurons that relay mechanical and chemical signals to the brain. Two new studies characterize the spinal sensory neurons that innervate the intestines and reveal a role for Piezo2 in these cells in sensing colonic distension and regulating gastrointestinal motility....

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Bibliographic Details
Published in:Current biology 2023-09, Vol.33 (18), p.R945-R947
Main Authors: Ly, Truong, Knight, Zachary A.
Format: Article
Language:English
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Summary:The gut is innervated by sensory neurons that relay mechanical and chemical signals to the brain. Two new studies characterize the spinal sensory neurons that innervate the intestines and reveal a role for Piezo2 in these cells in sensing colonic distension and regulating gastrointestinal motility. The gut is innervated by sensory neurons that relay mechanical and chemical signals to the brain. Two new studies characterize the spinal sensory neurons that innervate the intestines and reveal a role for Piezo2 in these cells in sensing colonic distension and regulating gastrointestinal motility.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2023.07.066