What do patients with Peyronie's disease expect from therapy? A prospective multi-center study

• Published in: Andrology (Oxford) 2024-05, Vol.12 (4), p.821-829
• Main Authors: Schäfer, Lukas, Cremers, Jann F, Witschel, Bahne, Schüttfort, Victor, Nieder, Timo O, König, Frederik, Vetterlein, Malte W, Gild, Philipp, Dahlem, Roland, Fisch, Margit, Kliesch, Sabine, Soave, Armin
• Format: Article
• Language: English
• Subjects: Connective tissue diseases; Surgery
• ISSN: 2047-2919; 2047-2927
• DOI: 10.1111/andr.13538

Little is known about patients' pre-treatment expectations in Peyronie's disease (PD). To evaluate in detail patients' expectations of conservative therapy and surgery. This multi-center study prospectively enrolled 317 PD patients, who were scheduled to receive conservative therapy or surgery between 2019 and 2022 at the Department of Urology of the University Medical Center Hamburg-Eppendorf, and the Center of Reproductive Medicine and Andrology, University Medical Center Muenster, both Germany. The primary end-point was patients' pre-treatment expectations of conservative therapy and surgery, measured with the Stanford Expectations of Treatment Scale (SETS). Secondary end-points included patient-reported psychological and physical symptoms, penile pain, symptom bother and erectile function, measured with the Peyronie's disease questionnaire (PDQ) and International Index of Erectile Function Erectile Function Domain (IIEF-EF). In total, 239 (75%) and 78 (25%) patients were scheduled for the conservative therapy and surgery, respectively. Patients undergoing surgery had higher positive and negative mean SETS expectations scores (14 vs. 11, p