Systemic and Ophthalmic Manifestations of Chikungunya Fever

• Published in: Ocular immunology and inflammation 2024-10, Vol.32 (8), p.1796-1803
• Main Authors: Mahendradas, Padmamalini, Patil, Aditya, Kawali, Ankush, Rathinam, Sivakumar R
• Format: Article
• Language: English
• Subjects: Chikungunya Fever - complications; Chikungunya Fever - diagnosis; Chikungunya virus; Eye Infections, Viral - diagnosis; Eye Infections, Viral - drug therapy; Eye Infections, Viral - etiology; Eye Infections, Viral - virology; Humans; Uveitis - diagnosis; Uveitis - drug therapy; Uveitis - etiology; Uveitis - virology
• ISSN: 0927-3948; 1744-5078; 1744-5078
• DOI: 10.1080/09273948.2023.2260464

Chikungunya is a re-emerging viral infection across the globe. The purpose of this article is to review the systemic and ophthalmic manifestations associated with chikungunya fever. A review of literature was conducted using online databases. In this report, we have reviewed the presently available literature on uveitis caused by chikungunya and highlighted the current knowledge of its clinical manifestations, imaging features, laboratory diagnostics, and the available therapeutic modalities from the systemic and ophthalmic standpoint. Ocular involvement in chikungunya infection may occur at the time of systemic manifestations or it may occur as a delayed presentation many weeks after the fever. Treatment relies on a supportive therapy for systemic illness. Treatment of ocular manifestation depends on the type of manifestations and usually includes a combination of topical and oral steroids.