Developmental outcome of children with Robin sequence treated with the current Paris protocol

Aim We aimed to investigate the developmental outcome of children with Robin sequence (RS) for whom continuous positive airway pressure was the main strategy to release upper airway obstruction. Methods We included children with isolated RS or RS associated with Stickler syndrome who were aged 15 mo...

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Bibliographic Details
Published in:Acta Paediatrica 2023-12, Vol.112 (12), p.2601-2610
Main Authors: Fleurance, Alix, Leunen, Dorothée, Végas, Nancy, Soupre, Véronique, Griffon, Lucie, Adnot, Pauline, Malecot, Gaelle, Luscan, Romain, Amiel, Jeanne, Fauroux, Brigitte, Abadie, Véronique
Format: Article
Language:English
Subjects:
Airway management
Children
Continuous positive airway pressure
Language
Mechanical ventilation
Phenotypes
Population studies
psychomotor development
Respiratory tract
Robin sequence
stickler syndrome
upper airway obstruction
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Summary:Aim We aimed to investigate the developmental outcome of children with Robin sequence (RS) for whom continuous positive airway pressure was the main strategy to release upper airway obstruction. Methods We included children with isolated RS or RS associated with Stickler syndrome who were aged 15 months to 6 years. We used the French version of the Child Development Inventory and calculated the developmental quotient (DQ) for eight different domains and the global DQ (DQ‐global). We searched for determinants of risk of delay. Results Of the 87 children, for 71%, the developmental evolution was within the norm (DQ‐global ≥86 or ≥−1 SD), 29% were at high risk of delay (DQ‐global
ISSN:0803-5253
1651-2227
DOI:10.1111/apa.16979