Paradoxical disease flare, skin infection and hypogammaglobulinaemia in patients with pemphigus vulgaris treated with rituximab

Patients with pemphigus vulgaris can develop hypogammaglobulinaemia after an infusion of rituximab, which manifests clinically as a paradoxical disease flare accompanying skin lesion infection.

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Bibliographic Details
Published in:Clinical and experimental dermatology 2024-01, Vol.49 (2), p.175-177
Main Authors: Padhiyar, Jignaben K, Patel, Nayan H, Lakum, Megha P, Patel, Jahnvi R, Patel, Kathak A, Patel, Harisiddhi B, Chaudhary, Prashant B
Format: Article
Language:English
Subjects:
Agammaglobulinemia - chemically induced
Antibodies, Monoclonal, Murine-Derived
Cellulitis
Humans
Immunologic Factors - adverse effects
Pemphigus - drug therapy
Rituximab - adverse effects
Skin Diseases, Infectious
Symptom Flare Up
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Description
Summary:Patients with pemphigus vulgaris can develop hypogammaglobulinaemia after an infusion of rituximab, which manifests clinically as a paradoxical disease flare accompanying skin lesion infection.
ISSN:0307-6938
1365-2230
DOI:10.1093/ced/llad347