Estimating the savings of a national project to prevent healthcare-associated infections in intensive care units

• Published in: The Journal of hospital infection 2024-01, Vol.143, p.8-17
• Main Authors: Oliveira, R.M.C., de Sousa, A.H.F., de Salvo, M.A., Petenate, A.J., Gushken, A.K.F., Ribas, E., Torelly, E.M.S., Silva, K.C.C.D., Bass, L.M., Tuma, P., Borem, P., Ue, L.Y., de Barros, C.G., Vernal, S.
• Format: Article
• Language: English
• Subjects: Bloodstream infection; Catheter-Related Infections - epidemiology; Catheter-Related Infections - prevention & control; Cross Infection - epidemiology; Cross Infection - prevention & control; Delivery of Health Care; Financial management; Healthcare-associated infections; Humans; Intensive care unit; Intensive Care Units; Pneumonia, Ventilator-Associated - epidemiology; Pneumonia, Ventilator-Associated - prevention & control; Prevention and control; Quality improvement; Urinary tract infection; Urinary Tract Infections - prevention & control; Ventilator-associated pneumonia
• ISSN: 0195-6701; 1532-2939
• DOI: 10.1016/j.jhin.2023.10.001

Healthcare-associated infections (HAIs) have a significant impact on patients' morbidity and mortality, and have a detrimental financial impact on the healthcare system. Various strategies exist to prevent HAIs, but economic evaluations are needed to determine which are most appropriate. To present the financial impact of a nationwide project on HAI prevention in intensive care units (ICUs) using a quality improvement (QI) approach. A health economic evaluation assessed the financial results of the QI initiative ‘Saúde em Nossas Mãos’ (SNM), implemented in Brazil between January 2018 and December 2020. Among 116 participating institutions, 13 (11.2%) fully reported the aggregate cost and stratified patients (with vs without HAIs) in the pre-intervention and post-intervention periods. Average cost (AC) was calculated for each analysed HAI: central-line-associated bloodstream infections (CLABSIs), ventilator-associated pneumonia (VAP) and catheter-associated urinary tract infections (CAUTIs). The absorption model and time-driven activity-based costing were used for cost estimations. The numbers of infections that the project could have prevented during its implementation were estimated to demonstrate the financial impact of the SNM initiative. The aggregated ACs calculated for each HAI from these 13 ICUs – US$8480 for CLABSIs, US$10,039 for VAP, and US$7464 for CAUTIs – were extrapolated to the total number of HAIs prevented by the project (1727 CLABSIs, 3797 VAP and 2150 CAUTIs). The overall savings of the SNM as of December 2020 were estimated at US$68.8 million, with an estimated return on investment (ROI) of 765%. Reporting accurate financial data on HAI prevention strategies is still challenging in Brazil. These results suggest that a national QI initiative to prevent HAIs in critical care settings is a feasible and value-based approach, reducing financial waste and yielding a significant ROI for the healthcare system.