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Application of 3D computed tomography in emphysematous parenchyma patients scheduled for bronchoscopic lung volume reduction
Bronchoscopic lung volume reduction (BLVR) is a feasible, safe, effective and minimally invasive technique to significantly improve the quality of life of advanced severe chronic obstructive pulmonary disease (COPD). In this study, three‐dimensional computed tomography (3D‐CT) automatic analysis sof...
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Published in: | Clinical and experimental pharmacology & physiology 2024-01, Vol.51 (1), p.10-16 |
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creator | Wei, Ping Tao, Ru‐Jia Lu, Hai‐wen Xu, Jin‐Fu Liu, Yi‐han Wang, Hai Li, Ling‐Ling Gu, Ye Cao, Wei‐Jun |
description | Bronchoscopic lung volume reduction (BLVR) is a feasible, safe, effective and minimally invasive technique to significantly improve the quality of life of advanced severe chronic obstructive pulmonary disease (COPD). In this study, three‐dimensional computed tomography (3D‐CT) automatic analysis software combined with pulmonary function test (PFT) was used to retrospectively evaluate the postoperative efficacy of BLVR patients. The purpose is to evaluate the improvement of lung function of local lung tissue after operation, maximize the benefits of patients, and facilitate BLVR in the treatment of patients with advanced COPD. All the reported cases of advanced COPD patients treated with BLVR with one‐way valve were collected and analysed from 2017 to 2020. Three‐dimensional‐CT image analysis software system was used to analyse the distribution of low‐density areas |
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In this study, three‐dimensional computed tomography (3D‐CT) automatic analysis software combined with pulmonary function test (PFT) was used to retrospectively evaluate the postoperative efficacy of BLVR patients. The purpose is to evaluate the improvement of lung function of local lung tissue after operation, maximize the benefits of patients, and facilitate BLVR in the treatment of patients with advanced COPD. All the reported cases of advanced COPD patients treated with BLVR with one‐way valve were collected and analysed from 2017 to 2020. Three‐dimensional‐CT image analysis software system was used to analyse the distribution of low‐density areas <950 Hounsfield units in both lungs pre‐ and post‐ BLVR. Meanwhile, all patients performed standard PFT pre‐ and post‐operation for retrospective analysis. We reported six patients that underwent unilateral BLVR with 1 to 3 valves according to the range of emphysema. All patients showed a median increase in forced expiratory volume in 1 second (FEV1) of 34%, compared with baseline values. Hyperinflation was reduced by 16.6% (range, 4.9%‐47.2%). The volumetric measurements showed a significant reduction in the treated lobe volume among these patients. Meanwhile, the targeted lobe volume changes were inversely correlated with change in FEV1/FEV1% in patients with heterogeneous emphysematous. We confirm that 3D‐CT analysis can quantify the changes of lung volume, ventilation and perfusion, to accurately evaluate the distribution and improvement of emphysema and rely less on the observer.</description><identifier>ISSN: 0305-1870</identifier><identifier>EISSN: 1440-1681</identifier><identifier>DOI: 10.1111/1440-1681.13822</identifier><identifier>PMID: 37806661</identifier><language>eng</language><publisher>Australia: Wiley Subscription Services, Inc</publisher><subject>3D computed tomography ; bronchoscopic lung volume reduction ; Chronic obstructive pulmonary disease ; Computed tomography ; Dimensional analysis ; Emphysema ; Image analysis ; Image processing ; Lung diseases ; Lungs ; Obstructive lung disease ; Parenchyma ; Pulmonary functions ; Quality of life ; Reduction ; Respiratory function ; Software ; Tomography</subject><ispartof>Clinical and experimental pharmacology & physiology, 2024-01, Vol.51 (1), p.10-16</ispartof><rights>2023 John Wiley & Sons Australia, Ltd.</rights><rights>2024 John Wiley & Sons Australia, Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3252-3893d5ab2e3bcf786360f5ba542e450542e6ea50158730c2076f37fd8ba015083</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37806661$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wei, Ping</creatorcontrib><creatorcontrib>Tao, Ru‐Jia</creatorcontrib><creatorcontrib>Lu, Hai‐wen</creatorcontrib><creatorcontrib>Xu, Jin‐Fu</creatorcontrib><creatorcontrib>Liu, Yi‐han</creatorcontrib><creatorcontrib>Wang, Hai</creatorcontrib><creatorcontrib>Li, Ling‐Ling</creatorcontrib><creatorcontrib>Gu, Ye</creatorcontrib><creatorcontrib>Cao, Wei‐Jun</creatorcontrib><title>Application of 3D computed tomography in emphysematous parenchyma patients scheduled for bronchoscopic lung volume reduction</title><title>Clinical and experimental pharmacology & physiology</title><addtitle>Clin Exp Pharmacol Physiol</addtitle><description>Bronchoscopic lung volume reduction (BLVR) is a feasible, safe, effective and minimally invasive technique to significantly improve the quality of life of advanced severe chronic obstructive pulmonary disease (COPD). In this study, three‐dimensional computed tomography (3D‐CT) automatic analysis software combined with pulmonary function test (PFT) was used to retrospectively evaluate the postoperative efficacy of BLVR patients. The purpose is to evaluate the improvement of lung function of local lung tissue after operation, maximize the benefits of patients, and facilitate BLVR in the treatment of patients with advanced COPD. All the reported cases of advanced COPD patients treated with BLVR with one‐way valve were collected and analysed from 2017 to 2020. Three‐dimensional‐CT image analysis software system was used to analyse the distribution of low‐density areas <950 Hounsfield units in both lungs pre‐ and post‐ BLVR. Meanwhile, all patients performed standard PFT pre‐ and post‐operation for retrospective analysis. We reported six patients that underwent unilateral BLVR with 1 to 3 valves according to the range of emphysema. All patients showed a median increase in forced expiratory volume in 1 second (FEV1) of 34%, compared with baseline values. Hyperinflation was reduced by 16.6% (range, 4.9%‐47.2%). The volumetric measurements showed a significant reduction in the treated lobe volume among these patients. Meanwhile, the targeted lobe volume changes were inversely correlated with change in FEV1/FEV1% in patients with heterogeneous emphysematous. We confirm that 3D‐CT analysis can quantify the changes of lung volume, ventilation and perfusion, to accurately evaluate the distribution and improvement of emphysema and rely less on the observer.</description><subject>3D computed tomography</subject><subject>bronchoscopic lung volume reduction</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Computed tomography</subject><subject>Dimensional analysis</subject><subject>Emphysema</subject><subject>Image analysis</subject><subject>Image processing</subject><subject>Lung diseases</subject><subject>Lungs</subject><subject>Obstructive lung disease</subject><subject>Parenchyma</subject><subject>Pulmonary functions</subject><subject>Quality of life</subject><subject>Reduction</subject><subject>Respiratory function</subject><subject>Software</subject><subject>Tomography</subject><issn>0305-1870</issn><issn>1440-1681</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNqFkUFP3DAQRq0KVLZLz71Vlrj0EhjbsWOOaEtbJCQ4wNlynAkbFMepnbRaqT--DgscuODLjEZvPtt6hHxhcMryOWNlCQVTmp0yoTn_QFavkwOyAgGyYLqCI_IppUcAkKDER3IkKg1KKbYi_y7Gse-cnbow0NBS8Z264Md5woZOwYeHaMftjnYDRZ-bhN5OYU50tBEHt915m9upw2FKNLktNnOfN9sQaR1DBkJyYewc7efhgf4J_eyRxky55cJjctjaPuHn57om9z8u7za_iuubn1ebi-vCCS55IfS5aKStOYratZVWQkEraytLjqWEpSi0EpjUlQDHoVKtqNpG1zbPQIs1-bbPHWP4PWOajO-Sw763A-bPGK6rUosKFM_oyRv0McxxyK8z_ByAsSd0Tc72lIshpYitGWPnbdwZBmYRYxYNZtFgnsTkja_PuXPtsXnlX0xkQO6Bv12Pu_fyzObydh_8HzX1mIY</recordid><startdate>202401</startdate><enddate>202401</enddate><creator>Wei, Ping</creator><creator>Tao, Ru‐Jia</creator><creator>Lu, Hai‐wen</creator><creator>Xu, Jin‐Fu</creator><creator>Liu, Yi‐han</creator><creator>Wang, Hai</creator><creator>Li, Ling‐Ling</creator><creator>Gu, Ye</creator><creator>Cao, Wei‐Jun</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>7U7</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>202401</creationdate><title>Application of 3D computed tomography in emphysematous parenchyma patients scheduled for bronchoscopic lung volume reduction</title><author>Wei, Ping ; 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In this study, three‐dimensional computed tomography (3D‐CT) automatic analysis software combined with pulmonary function test (PFT) was used to retrospectively evaluate the postoperative efficacy of BLVR patients. The purpose is to evaluate the improvement of lung function of local lung tissue after operation, maximize the benefits of patients, and facilitate BLVR in the treatment of patients with advanced COPD. All the reported cases of advanced COPD patients treated with BLVR with one‐way valve were collected and analysed from 2017 to 2020. Three‐dimensional‐CT image analysis software system was used to analyse the distribution of low‐density areas <950 Hounsfield units in both lungs pre‐ and post‐ BLVR. Meanwhile, all patients performed standard PFT pre‐ and post‐operation for retrospective analysis. We reported six patients that underwent unilateral BLVR with 1 to 3 valves according to the range of emphysema. All patients showed a median increase in forced expiratory volume in 1 second (FEV1) of 34%, compared with baseline values. Hyperinflation was reduced by 16.6% (range, 4.9%‐47.2%). The volumetric measurements showed a significant reduction in the treated lobe volume among these patients. Meanwhile, the targeted lobe volume changes were inversely correlated with change in FEV1/FEV1% in patients with heterogeneous emphysematous. We confirm that 3D‐CT analysis can quantify the changes of lung volume, ventilation and perfusion, to accurately evaluate the distribution and improvement of emphysema and rely less on the observer.</abstract><cop>Australia</cop><pub>Wiley Subscription Services, Inc</pub><pmid>37806661</pmid><doi>10.1111/1440-1681.13822</doi><tpages>7</tpages></addata></record> |
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subjects | 3D computed tomography bronchoscopic lung volume reduction Chronic obstructive pulmonary disease Computed tomography Dimensional analysis Emphysema Image analysis Image processing Lung diseases Lungs Obstructive lung disease Parenchyma Pulmonary functions Quality of life Reduction Respiratory function Software Tomography |
title | Application of 3D computed tomography in emphysematous parenchyma patients scheduled for bronchoscopic lung volume reduction |
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