Glycemic variability is associated with diastolic dysfunction in patients with type 2 diabetes

Abstract To investigate the relationship between glycemic variability (GV) and diastolic dysfunction in patients with type 2 diabetes mellitus (DM) without coronary artery disease. Seventy-eight patients with type 2 DM without coronary artery disease were enrolled into the study. Diastolic function...

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Published in:Journal of diabetes and its complications 2023-11, Vol.37 (11), p.108519-108519, Article 108519
Main Authors: Dzhun, Yana, Mankovsky, Georgy, Rudenko, Nadiya, Marushko, Yevgen, Saienko, Yanina, Mankovsky, Borys
Format: Article
Language:English
Subjects:
Age
Blood pressure
Body mass index
Cardiovascular disease
Continuous glucose monitoring
Coronary Artery Disease - complications
Coronary Artery Disease - epidemiology
Coronary vessels
Diabetes
Diabetes mellitus
Diabetes Mellitus, Type 2 - complications
Diastole
Diastolic dysfunction
Echocardiography
Glycemic variability
Heart failure
Heart Failure - complications
Humans
Insulin
Regression Analysis
Vein & artery diseases
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Summary:Abstract To investigate the relationship between glycemic variability (GV) and diastolic dysfunction in patients with type 2 diabetes mellitus (DM) without coronary artery disease. Seventy-eight patients with type 2 DM without coronary artery disease were enrolled into the study. Diastolic function was assessed by echocardiography (Philips IE33); GV was evaluated by continuous monitoring of glucose (CGM, Guardian™ Connect System, Medtronic). According to the GV all studied patients were divided into two groups: group I – standard deviation (SD) > 2 (high GV), n = 40; group II - SD ≤ 1.9 (normal GV), n = 38. Group I were older (49±9 vs 46±5; p
ISSN:1056-8727
1873-460X
DOI:10.1016/j.jdiacomp.2023.108519