Improved glycemic control after the use of flash glucose monitoring accompanied by improved treatment satisfaction in patients with non-insulin-treated type 2 diabetes: A post-hoc analysis of a randomized controlled trial

• Published in: Primary care diabetes 2023-12, Vol.17 (6), p.575-580
• Main Authors: Hayase, Ayaka, Onoue, Takeshi, Kobayashi, Tomoko, Wada, Eri, Handa, Tomoko, Kinoshita, Tamaki, Yamagami, Ayana, Yasuda, Yoshinori, Iwama, Shintaro, Kawaguchi, Yohei, Miyata, Takashi, Sugiyama, Mariko, Takagi, Hiroshi, Hagiwara, Daisuke, Suga, Hidetaka, Banno, Ryoichi, Kuwatsuka, Yachiyo, Ando, Masahiko, Goto, Motomitsu, Arima, Hiroshi
• Format: Article
• Language: English
• Subjects: Intermittently-scanned continuous glucose monitoring; Type 2 diabetes
• ISSN: 1751-9918; 1878-0210
• DOI: 10.1016/j.pcd.2023.09.009

In our previously reported randomized controlled trial in patients with noninsulin-treated type 2 diabetes, the use of flash glucose monitoring (FGM) improved glycated hemoglobin (HbA1c), and the improvement was sustained after the cessation of glucose monitoring. In this post-hoc analysis, we examined data from our trial to identify the factors that influenced FGM efficacy. We analyzed data for 48 of 49 participants of the FGM group who completed the trial to clarify the changes in various parameters and factors related to HbA1c improvement with the use of FGM. Analyses of the FGM data during the 12-week FGM provision period showed that the weekly mean blood glucose levels considerably decreased as early as at 1 week compared with the baseline values, and this decline continued for 12 weeks. An enhancement in the Diabetes Treatment Satisfaction Questionnaire regarding “willingness to continue the current treatment” score was significantly associated with the improvement in HbA1c at 12 (p = 0.009) and 24 weeks (p = 0.012). Glycemic control was improved soon after FGM initiation, accompanied by improved satisfaction with continuation of the current treatment in patients with noninsulin-treated type 2 diabetes. •Post-hoc analysis of an RCT examining FGM effect in insulin-naïve type 2 diabetes patients.•FGM use improved glycemic control as early as at 1 week of the sensor usage.•Changes in HbA1c was correlated with the percentage of time CGM is active.•HbA1c improvement was associated with the improvement of treatment satisfaction.