True intratracheal oxygen concentration delivered by SentriO Oxy™ masks under various respiratory conditions: a bench study

SentriO Oxy™ is a newly available, Food and Drug Administration-approved oxygenation mask system that provides high oxygenation, even on low-flow (5–10 L/min) oxygen. This study aimed to accurately measure the intratracheal fraction of inspired oxygen (FiO 2 ) using SentriO Oxy™ masks under relative...

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Bibliographic Details
Published in:Journal of clinical monitoring and computing 2023-12, Vol.37 (6), p.1489-1495
Main Authors: Chiang, Cheng, Teng, Wei-Nung, Chiang, Ting-Yun, Huang, Chao-Lan, Lin, Shi-Pin, Chang, Wen-Kuei, Ting, Chien-Kun
Format: Article
Language:English
Subjects:
Anesthesiology
Critical Care Medicine
Flow velocity
Health Sciences
Hypotheses
Intensive
Low flow
Masks
Medicine
Medicine & Public Health
Original Research
Oxygen
Oxygenation
Regression analysis
Respiratory rate
Statistics for Life Sciences
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Summary:SentriO Oxy™ is a newly available, Food and Drug Administration-approved oxygenation mask system that provides high oxygenation, even on low-flow (5–10 L/min) oxygen. This study aimed to accurately measure the intratracheal fraction of inspired oxygen (FiO 2 ) using SentriO Oxy™ masks under relatively low oxygen flow rates. A manikin-ventilator-test lung simulation system was used. We measured FiO 2 at the level of the carina, 5 minutes after applying 45 different respiratory parameter combinations using SentriO Oxy™ masks. Tidal volume (TV) was set to 300, 500, and 700 mL; respiratory rate (RR) was set to 8, 12, 16, 20, and 24 breaths per minute; and oxygen flow rate was set to 6, 8, and 10 L/min. Our hypothesis was that FiO 2 would be proportional to the difference between oxygen flow rate and minute ventilation. FiO 2 measured by smaller TV, lower RR, or higher oxygen flows revealed a significantly higher value, confirming our hypothesis. In addition, using linear regression analysis, we found that TV, RR, and oxygen flow were all significant factors influencing the measured FiO 2 . Our experiment proposed two prediction equations considering the oxygen flow rate, TV, and RR. The results of our study may provide information and prediction of FiO 2 for clinicians to use SentriO Oxy™ masks during sedative anesthetic procedures under low oxygen flow rates.
ISSN:1387-1307
1573-2614
DOI:10.1007/s10877-023-01076-4