Nanopore sequencing for malaria molecular surveillance: opportunities and challenges

Nanopore-based sequencing platforms offer the potential for affordable malaria molecular surveillance (MMS) in resource-limited settings to track and ultimately counteract emerging threats, such as drug resistance and diagnostic escape. Here, we discuss opportunities and challenges to implementing M...

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Bibliographic Details
Published in:Trends in parasitology 2023-12, Vol.39 (12), p.996-1000
Main Authors: Hamilton, William L., Ishengoma, Deus S., Parr, Jonathan B., Bridges, Daniel J., Barry, Alyssa E.
Format: Article
Language:English
Subjects:
antimalarial resistance
genomics
malaria
nanopore
surveillance
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Summary:Nanopore-based sequencing platforms offer the potential for affordable malaria molecular surveillance (MMS) in resource-limited settings to track and ultimately counteract emerging threats, such as drug resistance and diagnostic escape. Here, we discuss opportunities and challenges to implementing MMS using nanopore sequencing, highlighting priority areas for technical development and innovation. Nanopore-based sequencing platforms offer the potential for affordable malaria molecular surveillance (MMS) in resource-limited settings to track and ultimately counteract emerging threats, such as drug resistance and diagnostic escape. Here, we discuss opportunities and challenges to implementing MMS using nanopore sequencing, highlighting priority areas for technical development and innovation.
ISSN:1471-4922
1471-5007
DOI:10.1016/j.pt.2023.09.014