Childhood interstitial lung disease in Turkey: first data from the national registry

• Published in: European journal of pediatrics 2024-01, Vol.183 (1), p.295-304
• Main Authors: Nayır-Büyükşahin, Halime, Emiralioğlu, Nagehan, Kılınç, Ayşe Ayzıt, Girit, Saniye, Yalçın, Ebru, Şişmanlar Eyüboğlu, Tuğba, Çobanoğlu, Nazan, Cinel, Güzin, Pekcan, Sevgi, Gökdemir, Yasemin, Oğuz, Berna, Orhan, Diclehan, Doğru, Deniz, Özçelik, Uğur, Başkan, Azer Kılıç, Arslan, Hüseyin, Çokuğraş, Haluk, Onay, Zeynep Reyhan, Oksay, Sinem Can, Tortop, Deniz Mavi, Aslan, Ayşe Tana, Kekeç, Handan, Zirek, Fazılcan, Tekin, Merve Nur, Gülen, Figen, Girgin Dindar, Bahar, Eryılmaz Polat, Sanem, Uytun, Salih, Yılmaz, Aslı İmran, Ünal, Gökçen, Eralp, Ela Erdem, Karadağ, Bülent, Hangül, Melih, Köse, Mehmet, Özsezen, Beste, Çakır, Erkan, Bingöl, Ayşen, Hızal, Mina, Kartal Öztürk, Gökçen, Uyan, Zeynep Seda, Ramaslı Gürsoy, Tuğba, Serbes, Mahir, Kiper, Nural
• Format: Article
• Language: English
• Subjects: Bronchiectasis; Child; Childhood; Children; Diagnosis; Humans; Lung; Lung diseases; Lung Diseases, Interstitial - diagnosis; Lung Diseases, Interstitial - epidemiology; Lung Diseases, Interstitial - therapy; Lymphadenopathy; Medicine; Medicine & Public Health; Patients; Pediatrics; Population studies; Prospective Studies; Registries; Steroid hormones; Turkey - epidemiology
• ISSN: 1432-1076; 0340-6199; 1432-1076
• DOI: 10.1007/s00431-023-05290-9

The childhood interstitial lung diseases (chILD) Turkey registry (chILD-TR) was established in November 2021 to increase awareness of disease, and in collaboration with the centers to improve the diagnostic and treatment standards. Here, the first results of the chILD registry system were presented. In this prospective cohort study, data were collected using a data‐entry software system. The demographic characteristics, clinical, laboratory, radiologic findings, diagnoses, and treatment characteristics of the patients were evaluated. Clinical characteristics were compared between two main chILD groups ((A) diffuse parenchymal lung diseases (DPLD) disorders manifesting primarily in infancy [group1] and (B) DPLD disorders occurring at all ages [group 2]). There were 416 patients registered from 19 centers. Forty-six patients were excluded due to missing information. The median age of diagnosis of the patients was 6.05 (1.3–11.6) years. Across the study population ( n  = 370), 81 (21.8%) were in group 1, and 289 (78.1%) were in group 2. The median weight z -score was significantly lower in group 1 (− 2.0 [− 3.36 to − 0.81]) than in group 2 (− 0.80 [− 1.7 to 0.20]) ( p