Analysis of drug of abuse compounds using passive sampling and ultrahigh-liquid chromatography coupled to mass spectrometry

The present study proposes the monitoring of compounds of drugs of abuse through the use of passive samplers in water systems. Initially, four positive ion compounds of interest were determined according to national surveys, and then composite sampling and passive sampling were implemented using con...

Full description

Saved in:
Bibliographic Details
Published in:Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering Toxic/hazardous substances & environmental engineering, 2023, Vol.58 (12), p.943-953
Main Authors: Jiménez-Rojas, Carolina A., Gutiérrez Ulloa, Carlos Emilio, Chingaté-López, Sandra M., Lara-Borrero, Jaime A.
Format: Article
Language:English
Subjects:
Continuous flow
Drug abuse
Ecstasy
Liquid chromatography
Mass spectrometry
Mass spectroscopy
MDMA
Methamphetamine
Monitoring
Positive ions
River basins
Samplers
Sampling
Sorbents
Water analysis
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The present study proposes the monitoring of compounds of drugs of abuse through the use of passive samplers in water systems. Initially, four positive ion compounds of interest were determined according to national surveys, and then composite sampling and passive sampling were implemented using continuous-flow passive samplers containing two types of sorbents, the Empore disk and Gerstel Twister. Two study sites were established at the beginning and at the end of the middle Bogotá River basin. After 4 days, the sorbents were removed so that they could be desorbed and analyzed using UHPLC–MS in the laboratory. For the composite samples, the results were below the first calibration curve point (FCCP) of the chromatographic method, and for passive sampling, peaks of benzoylecgonine (BE) (21427.3 pg mL−1), methamphetamine (MET) (67101.5 pg mL−1), MDMA (ecstasy) (225844.8 pg mL−1) and 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) (15908.4 pg mL−1) were found. Therefore, passive sampling could be suggested as an alternative to composite sampling for the monitoring of compounds.
ISSN:1093-4529
1532-4117
DOI:10.1080/10934529.2023.2266327