Ecotoxicological effects of zinc oxide nanoparticles (ZnO-NPs) on aquatic organisms: Current research and emerging trends

• Published in: Journal of environmental management 2024-01, Vol.349, p.119396-119396, Article 119396
• Main Authors: Bordin, Eduarda Roberta, Ramsdorf, Wanessa Algarte, Lotti Domingos, Luana Maria, de Souza Miranda, Luís Phelipe, Mattoso Filho, Ney Pereira, Cestari, Marta Margarete
• Format: Article
• Language: English
• Subjects: Emerging contaminants; Green chemistry; Mechanism of action; Nanotoxicity
• ISSN: 0301-4797; 1095-8630
• DOI: 10.1016/j.jenvman.2023.119396

The rapid advancement of nanotechnology has contributed to the development of several products that are being released to the consumer market without careful analysis of their potential impact on the environment. Zinc oxide nanoparticles (ZnO-NPs) are used in several fields and are applied in consumer products, technological innovations, and biomedicine. In this sense, this study aims to compile existing knowledge regarding the effects of ZnO-NPs on non-target organisms, with the goal of ensuring the safety of human health and the environment. To achieve this objective, a systematic review of the available data on the toxicity of these nanomaterials to freshwater and marine/estuarine aquatic organisms was carried out. The findings indicate that freshwater invertebrates are the most commonly used organisms in ecotoxicological tests. The environmental sensitivity of the studied species was categorized as follows: invertebrates > bacteria > algae > vertebrates. Among the most sensitive species at each trophic level in freshwater and marine/estuarine environments are Daphnia magna and Paracentrotus lividus; Escherichia coli and Vibrio fischeri; Scenedesmus obliquus and Isochrysis galbana; and Danio rerio and Rutilus caspicus. The primary mechanisms responsible for the toxicity of ZnO-NPs involve the release of Zn2+ ions and the generation of reactive oxygen species (ROS). Thus, the biosynthesis of ZnO-NPs has been presented as a less toxic form of production, although it requires further investigation. Therefore, the synthesis of the information presented in this review can help to decide which organisms and which exposure concentrations are suitable for estimating the toxicity of nanomaterials in aquatic ecosystems. It is expected that this information will serve as a foundation for future research aimed at reducing the reliance on animals in ecotoxicological testing, aligning with the goal of promoting the sustainable advancement of nanotechnology. [Display omitted] •The toxicity of ZnO-NPs is mainly assessed using freshwater organisms.•The most sensitive organisms to ZnO-NPs are invertebrates D. magna and H. azteca.•Dissolution in Zn2+ ions is the main cause of ZnO-NPs toxicity.•Biosynthesis is an alternative to produce less toxic ZnO-NPs.