Ebola virus disease in children: epidemiology, pathogenesis, management, and prevention

Ebola disease is a severe disease with extremely high case-fatality rates ranging from 28–100%. Observations made during the 2013–2016 West African epidemic improved our understanding of the clinical course of Ebola disease and accelerated the study of therapeutic and preventative strategies. The ep...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric research 2024-01, Vol.95 (2), p.488-495
Main Authors: Dobbs, Katherine R., Lobb, Alyssa, Dent, Arlene E.
Format: Article
Language:English
Subjects:
Child
Disease Outbreaks - prevention & control
Disease prevention
Ebola virus
Ebolavirus
Epidemics - prevention & control
Epidemiology
Female
Hemorrhagic Fever, Ebola - epidemiology
Hemorrhagic Fever, Ebola - prevention & control
Humans
Medicine
Medicine & Public Health
Pathogenesis
Pediatric Surgery
Pediatrics
Pregnancy
Review Article
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Ebola disease is a severe disease with extremely high case-fatality rates ranging from 28–100%. Observations made during the 2013–2016 West African epidemic improved our understanding of the clinical course of Ebola disease and accelerated the study of therapeutic and preventative strategies. The epidemic also highlighted the unique challenges associated with providing optimal care for children during Ebola disease outbreaks. In this review, we outline current understanding of Ebola disease epidemiology, pathogenesis, management, and prevention, highlighting data pertinent to the care of children. Impact In this review, we summarize recent advancements in our understanding of Ebola disease epidemiology, clinical presentation, and therapeutic and preventative strategies. We highlight recent data pertinent to the care of children and pregnant women and identify research gaps for this important emerging viral infection in children.
ISSN:0031-3998
1530-0447
DOI:10.1038/s41390-023-02873-y