Optimising of axillary therapy in breast cancer: lessons from the past to plan for a better future

In this narrative review, we aim to explore the ability of radiation therapy to eradicate breast cancer regional node metastasis. It is a journey through data of older trials without systemic therapy showing the magnitude of axillary therapy (surgery versus radiation) on cancer control. Considering...

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Bibliographic Details
Published in:Radiologia medica 2024-02, Vol.129 (2), p.315-327
Main Authors: Kaidar-Person, Orit, Tramm, Trine, Kuehn, Thorsten, Gentilini, Oreste, Prat, Aleix, Montay-Gruel, Pierre, Meattini, Icro, Poortmans, Philip
Format: Article
Language:English
Subjects:
Diagnostic Radiology
Imaging
Interventional Radiology
Medicine
Medicine & Public Health
Neuroradiology
Optimization
Radiation therapy
Radiobiology
Radiology
Radiotherapy
Ultrasound
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Summary:In this narrative review, we aim to explore the ability of radiation therapy to eradicate breast cancer regional node metastasis. It is a journey through data of older trials without systemic therapy showing the magnitude of axillary therapy (surgery versus radiation) on cancer control. Considering that both systemic and loco-regional therapies were shown to reduce any recurrence with a complex interaction, our review includes surgical, radiation, and radiobiology consideration for breast cancer, and provide our view of future practise. The aim is to provide information optimise radiation therapy in the era of primary systemic therapy.
ISSN:1826-6983
0033-8362
1826-6983
DOI:10.1007/s11547-023-01743-1