Uterine collision tumor. Case report and review of the literature

• Published in: Revista colombiana de obstetricia y ginecología 2023-09, Vol.74 (3), p.225-236
• Main Authors: Ruiz-Echeverría, Franco Rafael, Beltrán-Salazar, María Islena, Caicedo-Páez, Lina María, Palencia-Palacios, Maribel, Salazar-Silva, Catherin, Viveros-Carreño, David
• Format: Article
• Language: eng ; spa
• Subjects: Adenocarcinoma - pathology; Colombia; Female; Humans
• ISSN: 2463-0225
• DOI: 10.18597/rcog.4011

To report the case of a patient with a uterine collision tumor and to conduct a review of the literature. A 76-year-old patient who presented to the national cancer referral center in Bogota (Colombia), where she was diagnosed with a uterine collision tumor consisting of a seroustype endometrial adenocarcinoma and a cervical adenosarcoma. The patient underwent surgical treatment followed by chemotherapy and supplemental radiotherapy, and died 16 months later. A search was conducted in the Medline via PubMed and Embase databases, including reports and case series of women with a diagnosis of uterine collision tumor, with retrieval of information regarding diagnosis, treatment and prognosis. A narrative summary of the findings was made. The search identified 36 titles, of which 14 studies with 17 patients were included. The most frequent histopathological diagnosis was endometrial adenocarcinoma and high and low grade endometrial sarcoma (47 %). Primary treatment was surgery and adjuvant treatment with chemotherapy and radiotherapy (15 %) was performed in close to 50 % of cases. One-year survival was 75 %. No cases of uterine collision tumors with the histopathology or in the location of the reported case were found in the literature. If this reported case is taken into account, 2-year mortality is 28 %. Further studies to describe the immunohistochemistry, treatment and prognosis of this condition are needed.