Survey-based assessment of hematopoietic stem cell graft manipulation (minimal) by cell therapy labs supporting hematopoietic stem cell transplants in India

Hematopoietic stem cell transplants (HSCTs) are increasingly being offered to patients in India for various conditions. The Indian Stem Cell Transplant Registry shows that a total of 2533 transplants were done in India in 2019. An epidemiological descriptive cross-sectional survey (55 questions) of...

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Bibliographic Details
Published in:Cytotherapy (Oxford, England) England), 2024-01, Vol.26 (1), p.96-102
Main Authors: Arora, Satyam, Setia, Rasika, Sharma, Sanjeev, Dua, Seema, Dogra, Mitu, Radhakrishnan, Nita, Bakliwal, Anamika
Format: Article
Language:English
Subjects:
Adolescent
Child
Cross-Sectional Studies
Dimethyl Sulfoxide
Freezing
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells
Humans
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Summary:Hematopoietic stem cell transplants (HSCTs) are increasingly being offered to patients in India for various conditions. The Indian Stem Cell Transplant Registry shows that a total of 2533 transplants were done in India in 2019. An epidemiological descriptive cross-sectional survey (55 questions) of centers providing HSCT in India was planned to analyze variations in policies and practices regarding HSCT graft manipulation (i.e., plasma reduction, red blood cell [RBC] depletion and cryopreservation). A total of 63 of 102 centers responded to the survey (response rate, 61.7%), mostly from the northern part of India (27 of 63 [42.8%]). The majority of responding centers reported performing >50 HSCTs annually (n = 24 [38%]), and 92% (58 of 63) performed stem cell collections from a pediatric donor/patient (age
ISSN:1465-3249
1477-2566
DOI:10.1016/j.jcyt.2023.10.006