Siloxane surfactants in polymer nanoparticles formulation

• Published in: Applied organometallic chemistry 2006-04, Vol.20 (4), p.235-245
• Main Authors: Racles, Carmen, Hamaide, Thierry, Ioanid, Aurelia
• Format: Article
• Language: English
• Subjects: anionic surfactants; Applied sciences; Exact sciences and technology; Forms of application and semi-finished materials; hydrosilylation; ion exchanger; Miscellaneous; monosaccharide; nanoprecipitation; nonionic surfactants; Polymer industry, paints, wood; siloxane; Technology of polymers
• ISSN: 0268-2605; 1099-0739
• DOI: 10.1002/aoc.1051

Carbohydrate‐modified cyclosiloxanes were synthesized by hydrosilylation reactions of protected allyl‐monosaccharides and subsequent deprotection with a gel‐type ion exchanger. They were characterized by 1H and 13C‐NMR, FT‐IR, GPC and surface tension measurements. These compounds, as well as other water soluble, carboxylate‐based siloxanes were tested as stabilizers in nanoparticle formulations, with polydimethylsiloxane (PDMS), poly(ε‐caprolactone) (PCL) and UDEL polysulfone (PSF) as polymer cores. Owing to their low critical micelle concentrations (cmc), small amounts of surfactants were required. The particle size and granulometric distribution were measured by dynamic light scattering (DLS). Electron microscopy confirmed the DLS results and revealed aggregation phenomena in dry state, depending on the polymer core. In the tested conditions, the glass transition temperature of the polymer seems to be the driving force for the stability of dry nanoparticles. Copyright © 2006 John Wiley & Sons, Ltd. Monosaccharide‐modified cyclosiloxanes were synthesized and characterized. These compounds, as well as potassium salts of sebacomethyldisiloxanes were used as surfactants in nanoprecipitation of polycaprolactone, polysiloxane and polysulfone. Particles of 100–400 nm diameter were obtained, depending on surfactant and polymer core.