Is shorter antibiotic treatment duration increasing the risk of relapse in paediatric acute focal bacterial nephritis?

Table 1 Summary of literature search First author, journal, year Study group (population and comparisons) Study type (level of evidence Oxford CEBM) Outcome Key result numbers Comments Cheng, Pediatric Infectious Disease Journal, 201010 109 children with AFBN diagnosed with CT 109 children with APN...

Full description

Saved in:
Bibliographic Details
Published in:Archives of disease in childhood 2024-03, Vol.109 (3), p.248-250
Main Authors: Vaezipour, Nina, Evers, Katrina, Schmid, Hanna, Ritz, Nicole, Goischke, Alexandra
Format: Article
Language:English
Subjects:
Abscesses
Antibiotics
Antimicrobial agents
Antimicrobial resistance
Archimedes
Bacterial infections
Bladder
Children
Cohort analysis
Communicable Diseases
Computed tomography
Constipation
Dimercaptosuccinic acid
Ethics
Evidence
Failure
High temperature
Individualized Instruction
infectious disease medicine
Infectious diseases
Inflammation
Kidneys
Lesions
Medical treatment
nephrology
paediatrics
Patients
Pediatrics
Periodicals
Persistence
Population studies
Procalcitonin
Pyelonephritis
Radiation
Randomized Controlled Trials
Renal failure
Scintigraphy
Systematic review
Ultrasonic imaging
Ultrasound
Urinary tract
Urinary tract infections
Urination
Urine
Urogenital system
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Table 1 Summary of literature search First author, journal, year Study group (population and comparisons) Study type (level of evidence Oxford CEBM) Outcome Key result numbers Comments Cheng, Pediatric Infectious Disease Journal, 201010 109 children with AFBN diagnosed with CT 109 children with APN as comparators Reference standard was dimercaptosuccinic acid scintigraphy at least 6 months later to assess renal scarring RCT comparing antibiotic treatment 2–3 weeks (level 2) Relapse/treatment failure rate Incidence of renal scarring 9/68 (13%) treatment failure or relapse in 2-week arm 1/63 (2%) treatment failure in 3-week arm AFBN 97/109 (89%) OR 15 p
ISSN:0003-9888
1468-2044
DOI:10.1136/archdischild-2023-326054