UMG1/CD3ε‐bispecific T‐cell engager redirects T‐cell cytotoxicity against diffuse large B‐cell lymphoma

Summary UMG1 is a unique epitope of CD43, not expressed by normal cells and tissues of haematopoietic and non‐haematopoietic origin, except thymocytes and a minority (

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Bibliographic Details
Published in:British journal of haematology 2024-02, Vol.204 (2), p.555-560
Main Authors: Caracciolo, Daniele, Polerà, Nicoletta, Belmonte, Beatrice, Conforti, Francesco, Signorelli, Stefania, Gulino, Alessandro, Staropoli, Nicoletta, Tuccillo, Franca Maria, Bonelli, Patrizia, Juli, Giada, Grillone, Katia, Ascrizzi, Serena, Cirillo, Maria, Migale, Leonardo, Ballerini, Andrea, Pelizon, Cristina, Di Martino, Maria Teresa, Tagliaferri, Pierosandro, Riillo, Caterina, Tassone, Pierfrancesco
Format: Article
Language:English
Subjects:
bispecific T‐cell engager
BTCE
CD43
CD43 antigen
Cytotoxicity
DLBCL
Epitopes
Humans
Immunohistochemistry
immunotherapy
Lymphocytes T
Lymphoma
Lymphoma, Large B-Cell, Diffuse - pathology
Peripheral blood
T-Lymphocytes - metabolism
Thymocytes
UMG1
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Description
Summary:Summary UMG1 is a unique epitope of CD43, not expressed by normal cells and tissues of haematopoietic and non‐haematopoietic origin, except thymocytes and a minority (
ISSN:0007-1048
1365-2141
DOI:10.1111/bjh.19183