Diagnostic delay and its associated factors in Chinese axial spondyloarthritis: A single‐center study of 1295 patients

Aim To delineate the landscape of diagnostic delay in Chinese axial spondyloarthritis (axSpA), investigate its associated factors, and explore its potential impact on medication modalities. Methods A total of 1295 patients fulfilling the ASAS classification criteria were obtained. Demographic and cl...

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Bibliographic Details
Published in:International journal of rheumatic diseases 2024-01, Vol.27 (1), p.e14975-n/a
Main Authors: Zheng, Xuqi, Chen, Zena, Wu, Xinyu, Xie, Ya, Wu, Jialing, Xiao, Min, Yang, Mingcan, Tu, Liudan, Cao, Shuangyan, Wei, Qiujing, Gu, Jieruo
Format: Article
Language:English
Subjects:
axial spondyloarthritis
diagnostic delay
misdiagnosis
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Summary:Aim To delineate the landscape of diagnostic delay in Chinese axial spondyloarthritis (axSpA), investigate its associated factors, and explore its potential impact on medication modalities. Methods A total of 1295 patients fulfilling the ASAS classification criteria were obtained. Demographic and clinical data were collected through face‐to‐face interviews, based on predesigned questionnaires and available medical records. Logistic regression analyses under univariate and multivariable model were performed, using the median of diagnostic delay as the cut‐off point for group classification. Differences between early‐ and late‐diagnosed groups were subsequently compared by the Pearson chi‐square test or Mann–Whitney U test. Results Of 1295 axSpA patients, 80.3% were male and the median of disease duration was 8.0 years. The median (IQR) diagnostic delay in Chinese axSpA was 3.0 (1.0 ~ 7.0) years and 24.8% of them reported a history of misdiagnosis. Older age at onset (OR = 0.97, p 
ISSN:1756-1841
1756-185X
DOI:10.1111/1756-185X.14975