Cytokine removal: do not ban it, but learn in whom and when to use it

[1], who raised some issues regarding our manuscript “Efficacy of Cytosorb®-a systematic review and meta-analysis.” [...]mortality is the most relevant endpoint and it is the ideal endpoint for a meta-analysis, as it is easy to measure and there is little variation in the way it is assessed. [...]we...

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Bibliographic Details
Published in:Critical care (London, England) England), 2023-11, Vol.27 (1), p.1-444, Article 444
Main Authors: Schmidt, Bernhard M. W, Lang, H, Tian, Z. J, Becker, S, Melk, A
Format: Article
Language:English
Subjects:
Critical care
Cytokines
Intensive care
Medicine
Mortality
Patients
Sepsis
Citations: Items that this one cites
Online Access:Get full text
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Summary:[1], who raised some issues regarding our manuscript “Efficacy of Cytosorb®-a systematic review and meta-analysis.” [...]mortality is the most relevant endpoint and it is the ideal endpoint for a meta-analysis, as it is easy to measure and there is little variation in the way it is assessed. [...]we have the obligation to perform RCTs in properly selected patients, taking into account the natural course of the respective disease in order to give us enough evidence for the safe usage of the device to the benefit of our patients.
ISSN:1364-8535
1364-8535
1366-609X
1466-609X
DOI:10.1186/s13054-023-04736-8