Diagnostic performance of the cingulate island sign ratio for differentiating dementia with Lewy bodies from Alzheimer's disease changes depending on the mini-mental state examination score

The cingulate island sign (CIS) ratio is a diagnostic adjunct for differentiating dementia with Lewy bodies (DLB) from Alzheimer's disease (AD). A recent study showed that the CIS ratio in DLB changed depending on the Mini-Mental State Examination (MMSE) score. We aimed to evaluate whether the...

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Bibliographic Details
Published in:Journal of the neurological sciences 2023-12, Vol.455, p.122782-122782, Article 122782
Main Authors: Asahara, Yuki, Kameyama, Masashi, Ishii, Kenji, Ishibashi, Kenji
Format: Article
Language:English
Subjects:
Alzheimer Disease - diagnostic imaging
Diagnosis, Differential
Fluorodeoxyglucose F18
Humans
Lewy Body Disease - diagnostic imaging
ROC Curve
Sensitivity and Specificity
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Summary:The cingulate island sign (CIS) ratio is a diagnostic adjunct for differentiating dementia with Lewy bodies (DLB) from Alzheimer's disease (AD). A recent study showed that the CIS ratio in DLB changed depending on the Mini-Mental State Examination (MMSE) score. We aimed to evaluate whether the diagnostic performance (sensitivity and specificity) of the CIS ratio for differentiating DLB from AD changes depending on the MMSE score. Twenty-two patients with DLB and 26 amyloid-positive patients with AD, who underwent F-FDG PET and completed an MMSE examination, were classified into three groups according to MMSE scores: Group A (MMSE >24), Group B (20 ≤ MMSE ≤24), and Group C (MMSE
ISSN:0022-510X
1878-5883
DOI:10.1016/j.jns.2023.122782