All-cause mortality and risk factors in patients with type 1 diabetes in Castilla-La Mancha, Spain. DIACAM1 2010–2020 study

• Published in: Primary care diabetes 2024-02, Vol.18 (1), p.59-64
• Main Authors: Pinés Corrales, Pedro José, Sastre Marcos, Julia, López Gallardo, Gema, Moreno Fernández, Jesús, Herranz Antolín, Sandra, Quiroga López, Iván, Del Val Zaballos, Florentino, González López, Javier, Alfaro Martínez, José Joaquín
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Cardiovascular Diseases - diagnosis; Cardiovascular Diseases - epidemiology; Creatinine; Cross-Sectional Studies; Diabetes mellitus; Diabetes Mellitus, Type 1 - diagnosis; Diabetes Mellitus, Type 1 - drug therapy; Follow-Up Studies; Glycated Hemoglobin; Humans; Mortality; Retinal Diseases - complications; Risk Factors; Spain - epidemiology; Survival; Type 1
• ISSN: 1751-9918; 1878-0210
• DOI: 10.1016/j.pcd.2023.11.003

Despite better treatments and care for patients with type 1 diabetes (T1DM), all-cause and cardiovascular mortality still remains higher compared to the general population. We evaluated mortality and risk factors for mortality in a representative cohort of patients with T1DM. DIACAM1 was a cross-sectional, multicenter study on adult patients (≥ 16 years old) and diabetes with at least 5 years since diabetes diagnosis conducted between 2009 and 2010. DIACAM1 2010–2020 study was a follow-up study, extension of DIACAM1, where vital status of patients was evaluated between June 2019 and June 2020. 4.03% [CI95%, 2.53–5.62) of the 1465 patients with T1DM included in the cohort of the DIACAM1 in 2010 had died. Survival was lower than in the sex- and age-matched general population in the same region. 40.7% of deaths were due to cardiovascular disease. HbA1c levels