Tubulointerstitial Nephritis and Uveitis Syndrome in Pediatric Patients

Tubulointerstitial nephritis and uveitis (TINU) syndrome is a disorder that was originally described in 1975. The syndrome, although diagnosed in all age ranges, is more frequently reported in pediatric patients. Diagnosis can be difficult, and its clinical spectrum is still being defined. In this a...

Full description

Saved in:
Bibliographic Details
Published in:Ocular immunology and inflammation 2023-12, Vol.31 (10), p.1955-1964
Main Authors: Janetos, Timothy M, Lee, Ping Hei Alfie, Goldstein, Debra A
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Tubulointerstitial nephritis and uveitis (TINU) syndrome is a disorder that was originally described in 1975. The syndrome, although diagnosed in all age ranges, is more frequently reported in pediatric patients. Diagnosis can be difficult, and its clinical spectrum is still being defined. In this article, we review the epidemiology, diagnosis, pathogenesis, clinical findings, prognosis, and treatment of both the ocular and renal disease. We comment on the current difficulties in diagnosis and study of the disease, its expanding clinical spectrum, and treatment strategies in pediatric patients.
ISSN:0927-3948
1744-5078
DOI:10.1080/09273948.2023.2279689