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How we do it: the Zurich Microsurgery Lab technique for placenta preparation

Background Perfused placentas provide an excellent and accessible model for microvascular dissection, microsuturing and microanastomosis training — particularly in the early microsurgical learning curve. This way, a significant amount of live animals can be spared. Method We present the Zurich Micro...

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Bibliographic Details
Published in:Acta neurochirurgica 2023-12, Vol.165 (12), p.3821-3824
Main Authors: Höbner, Lara Maria, Staartjes, Victor E., Colombo, Elisa, Sebök, Martina, Regli, Luca, Esposito, Giuseppe
Format: Article
Language:English
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Summary:Background Perfused placentas provide an excellent and accessible model for microvascular dissection, microsuturing and microanastomosis training — particularly in the early microsurgical learning curve. This way, a significant amount of live animals can be spared. Method We present the Zurich Microsurgery Lab protocol, detailing steps for obtaining, selecting, cleaning, flushing, cannulating, and preserving human placentas — as well as microsurgical training examples — in a tried-and-true, safe, cost-effective, and high-yield fashion. Conclusion Our technique enables highly realistic microsurgical training (microdissection, microvascular repair, microanastomosis) based on readily available materials. Proper handling, preparation, and preservation of the perfused placenta models is key.
ISSN:0942-0940
0001-6268
0942-0940
DOI:10.1007/s00701-023-05847-5