Advancing Strongyloides omics data: bridging the gap with Caenorhabditis elegans

Among nematodes, the free-living model organism boasts the most advanced portfolio of high-quality omics data. The resources available for parasitic nematodes, including spp., however, are lagging behind. While remains the most tractable nematode and has significantly advanced our understanding of m...

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Bibliographic Details
Published in:Philosophical transactions of the Royal Society of London. Series B. Biological sciences 2024-01, Vol.379 (1894), p.20220437-20220437
Main Authors: Al-Jawabreh, Reem, Lastik, Dominika, McKenzie, Darrin, Reynolds, Kieran, Suleiman, Mona, Mousley, Angela, Atkinson, Louise, Hunt, Vicky
Format: Article
Language:English
Subjects:
Animals
Caenorhabditis elegans - genetics
Nematoda
Strongyloides
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Summary:Among nematodes, the free-living model organism boasts the most advanced portfolio of high-quality omics data. The resources available for parasitic nematodes, including spp., however, are lagging behind. While remains the most tractable nematode and has significantly advanced our understanding of many facets of nematode biology, is not suitable as a surrogate system for the study of parasitism and it is important that we improve the omics resources available for parasitic nematode species. Here, we review the omics data available for spp and compare the available resources to those for and other parasitic nematodes. The advancements in omics offer a blueprint for improving omics-led research in . We suggest areas of priority for future research that will pave the way for expansions in omics resources and technologies. This article is part of the Theo Murphy meeting issue ' : omics to worm-free populations'.
ISSN:0962-8436
1471-2970
DOI:10.1098/rstb.2022.0437