Dynamically resizable nanometre-scale apertures for molecular sensing

An easily fabricated resizable nanometre-scale aperture provides a novel class of electrical device that can be deployed as a tunable molecular sensor. Here, we demonstrate that the metered penetration of an elastomeric membrane with a sharp probe yields an aperture that, by reversible adjustment of...

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Bibliographic Details
Published in:Sensors and actuators. B, Chemical Chemical, 2007-04, Vol.123 (1), p.325-330
Main Authors: Sowerby, Stephen J., Broom, Murray F., Petersen, George B.
Format: Article
Language:English
Subjects:
Actuators
Adjustable
Apertures
Coulter
Deoxyribonucleic acid
Devices
DNA
Gating and risering
Membranes
Nanopore
Penetration
Sensor
Sensors
Stochastic
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Summary:An easily fabricated resizable nanometre-scale aperture provides a novel class of electrical device that can be deployed as a tunable molecular sensor. Here, we demonstrate that the metered penetration of an elastomeric membrane with a sharp probe yields an aperture that, by reversible adjustment of the membrane, provides a spectrum of geometries suitable for single particle analysis. We describe such an aperture optimised in situ for the detection and controlled gating of DNA molecules.
ISSN:0925-4005
1873-3077
DOI:10.1016/j.snb.2006.08.031