Massive Localized Lymphedema: Two Case Studies and Diagnostic Challenges

Massive localized lymphedema (MLL) is an emerging clinical phenomenon predominantly observed in morbidly obese individuals. It presents both diagnostic and therapeutic challenges to clinicians due to its characterization by large, pendulous masses in the abdomen or thigh. MLL may resemble malignant...

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Published in:Cureus 2023, Vol.15 (10), p.e47092-e47092
Main Authors: Ba-Shammakh, Saleh A, Haj-Freej, Hasn M, Al-Naggar, Yanof S, Ghanem, Waleed, Haij, Manal Z, Al-Mohd, Fahmi, Hijazi, Eman, Amr, Samir S
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container_title Cureus
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creator Ba-Shammakh, Saleh A
Haj-Freej, Hasn M
Al-Naggar, Yanof S
Ghanem, Waleed
Haij, Manal Z
Al-Mohd, Fahmi
Hijazi, Eman
Amr, Samir S
description Massive localized lymphedema (MLL) is an emerging clinical phenomenon predominantly observed in morbidly obese individuals. It presents both diagnostic and therapeutic challenges to clinicians due to its characterization by large, pendulous masses in the abdomen or thigh. MLL may resemble malignant conditions, such as liposarcoma, leading to unnecessary invasive interventions. This study presents two case studies: a 74-year-old male who succumbed to postoperative complications and a 56-year-old female who experienced successful recovery. These cases highlight the urgent need for robust diagnostic criteria and evidence-based management approaches for MLL. In addition, further research exploring the pathogenesis, risk factors, and potential connections among MLL, hypothyroidism, and angiosarcoma is essential.
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title Massive Localized Lymphedema: Two Case Studies and Diagnostic Challenges
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