Prenatal ultrasound screening and pregnancy outcomes in HIV-positive women in Germany: results from a retrospective single-center study at the Charité-Universitätsmedizin Berlin

Objectives The aim of this study was to investigate the rate of Mother-to-child-transmission (MTCT) in women living with HIV (WLWH) in a tertiary care institution. Furthermore, we aimed to assess prenatal ultrasound screening for fetal anomalies and outcomes in high-risk pregnancies due to maternal...

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Published in:Archives of gynecology and obstetrics 2024-09, Vol.310 (3), p.1385-1395
Main Authors: Hofacker, Maja, Weichert, Alexander, Feiterna-Sperling, Cornelia, von Weizsäcker, Katharina, Siedentopf, Jan-Peter, Heinrich-Rohr, Michaela, Henrich, Wolfgang, Rohr, Irena
Format: Article
Language:English
Subjects:
Adult
Cesarean Section - statistics & numerical data
Congenital Abnormalities - diagnostic imaging
Congenital Abnormalities - epidemiology
Disease transmission
Endocrinology
Female
Germany - epidemiology
Gynecology
HIV
HIV Infections - drug therapy
Human Genetics
Human immunodeficiency virus
Humans
Infant, Newborn
Infectious Disease Transmission, Vertical - prevention & control
Infectious Disease Transmission, Vertical - statistics & numerical data
Maternal-Fetal Medicine
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Pregnancy
Pregnancy Complications, Infectious - epidemiology
Pregnancy Outcome
Prenatal care
Retrospective Studies
Ultrasonic imaging
Ultrasonography, Prenatal - statistics & numerical data
Womens health
Young Adult
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Summary:Objectives The aim of this study was to investigate the rate of Mother-to-child-transmission (MTCT) in women living with HIV (WLWH) in a tertiary care institution. Furthermore, we aimed to assess prenatal ultrasound screening for fetal anomalies and outcomes in high-risk pregnancies due to maternal HIV infection.” Methods In this single-center study, retrospective data related to pregnancy and childbirth were collected from 420 WLWH. All data were evaluated descriptively. Results From January 2014 to December 2020, a total number of 420 pregnant WLWH delivered 428 newborns. 415 (98.8%) were receiving antiretroviral therapy (ART) and 88.8% had a viral load of 
ISSN:1432-0711
0932-0067
1432-0711
DOI:10.1007/s00404-023-07286-0