Biodegradable and biocompatible collagen-based hybrid materials for force sensing applications

With the aim of replacing synthetic macromolecules by biological macromolecules for advanced applications, collagen films were produced with two different ionic liquids (ILs), choline dihydrogen phosphate ([Ch][DHP]) and choline serinate ([Ch][Seri]), added in order to modulate the electrical respon...

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Bibliographic Details
Published in:International journal of biological macromolecules 2024-01, Vol.256 (Pt 2), p.128486-128486, Article 128486
Main Authors: Andonegi, Mireia, Meira, Rafaela M., Correia, Daniela M., Pereira, Nelson, Costa, Carlos M., Lanceros-Mendez, Senentxu, de la Caba, Koro, Guerrero, Pedro
Format: Article
Language:English
Subjects:
Collagen
Electrical response
Pressure sensor
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Summary:With the aim of replacing synthetic macromolecules by biological macromolecules for advanced applications, collagen films were produced with two different ionic liquids (ILs), choline dihydrogen phosphate ([Ch][DHP]) and choline serinate ([Ch][Seri]), added in order to modulate the electrical responses. The films were prepared by casting, varying IL content between 0 and 6 wt%. The morphology and thermal properties of the resulting films were found to be independent of both IL type and content. However, the highest direct curret (d.c.) electrical conductivity (1.4 × 10−8 S·cm−1) was achieved for collagen films containing 3 wt% [Ch][DHP]. Furthermore, it was demonstrated that IL/collagen films were non-cytotoxic, with cell activity values exceeding 70 %. These collagen films were proven to be suitable for force sensing applications, displaying excellent sensitivity and stability upon repeated testing.
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2023.128486